In immediately’s health-conscious world, dietary dietary supplements have turn out to be a well-liked instrument for filling dietary gaps, bettering total well-being, and even managing particular well being situations. Nonetheless, not all dietary supplements are created equal. Some will be contaminated, work together with medicines, and even hurt liver well being. Choosing the proper complement requires cautious consideration and consciousness of potential dangers, and it additionally means being conscious of shady advertising and marketing techniques!
‘Dietary supplements’ is an umbrella time period for supplemental types of particular person vitamins like calcium and iron. However the extra problematic of the bunch are ‘pure’ dietary dietary supplements which can be marketed with shady claims, proprietary formulation, and little to no testing. These are the kinds of dietary supplements that I’m principally referring to on this publish.
The Hidden Risks of Dietary supplements: Liver Failure, Latest Analysis, and How one can Keep Secure
Dietary dietary supplements are a multi-billion-dollar business, marketed as a straightforward method to enhance well being, improve vitality, and fill in dietary gaps. Nonetheless, behind the shiny labels and well being claims, a rising physique of analysis reveals that some dietary supplements can pose severe well being dangers—together with liver failure.

In recent times, circumstances of supplement-induced liver damage (SILI) have been on the rise, with sure natural and dietary dietary supplements linked to extreme liver harm, hospitalization, and even demise. Regardless of being broadly obtainable over-the-counter and infrequently perceived as “pure” and protected, many dietary supplements are poorly regulated and may comprise dangerous elements.
Complement Advertising and marketing is a Dumpster Fireplace
‘Nevertheless it’s pure!’ So are toxic mushrooms, however no person desires to eat these. The complement business – specifically the vitamin complement business – is constructed on convincing individuals to purchase dietary supplements that we truly don’t want.
Implying that dietary supplements are extra ‘pure’ than medicines works on the Attraction to Nature fallacy, which complement makers use to make their product seem safer than prescribed drugs. As a dietitian, I’m seeing this quite a bit with GLP-1 dietary supplements, that are principally simply rubbish. Nothing about them is efficient or safer than precise medicines, that are regulated and prescribed beneath managed situations (ideally…everyone knows one thing who’s getting them from doubtful sources).
I used to be unreasonably completely satisfied to see that Kourtney Kardashian’s Lemme GLP-1 complement is at present the topic of a category motion lawsuit for claiming to work like GLP-1 agonist remedy. It doesn’t. However as I wrote in considered one of my current posts, there are lots of individuals who need GLP-1 remedy however can’t afford it. This leaves a spot that’s being grossly exploited by the complement business.


That’s how shady complement makers earn their cash, and it typically works…to the tune of $177 billion {dollars} in 2023, and projected to develop exponentially for the forseeable future. Whether or not it’s weight reduction, menopause, blood sugar (see my Glucose Goddess Anti Spike evaluation right here), immunity-boosting, or no matter else, the complement business has a tablet for that.
It goes with out saying that if a complement is claiming to remedy anxiousness or despair or another psychological well being prognosis, it’s an enormous pink flag. Claims like these are unethical and probably harmful, as they’ll persuade individuals to desert efficient and mandatory remedy.
Getting sensible to complement advertising and marketing scams takes a couple of small checks.
Diet Complement Pink Flags:
No analysis, or basing claims on animal or cell analysis. Even for those who aren’t well-versed in studying analysis, at all times check out the complement’s web site to see if it presents analysis to again up its claims. Is the analysis executed on people? Animals? How previous are the research? Is the analysis executed on the product itself, or solely on sure elements that the product accommodates?
I wrote a publish about the fundamentals of decoding vitamin analysis right here, however the TL;DR is that you really want current research (as in, final 5 years), executed in people, revealed in peer-reviewed journals, on the product itself. 99% of the time, you received’t discover all of these issues. That could be a pink flag.
Something bought by multi-level advertising and marketing. Not solely do MLM corporations prey on susceptible individuals (primarily girls), they have a tendency to take advantage of egregious claims about their merchandise. MLM salespeople are usually not educated to offer vitamin recommendation or perceive your well being historical past. Belief me – if one thing groundbreaking exists, it is going to be regulated by the FDA and bought in drugstores, not by some MLM coach.


Implying that their system was found by ‘Harvard (or X Ivy League) scientists’ or that Huge Pharma/precise scientists haven’t but found this groundbreaking secret. I see this quite a bit from corporations like VShred (learn my VShred evaluation right here) and Lifevantage (learn my Lifevantage Protandim and GLP-1 evaluation right here), amongst many others. There is no such thing as a huge secret. No person is hiding something (in addition to these corporations attempting to cover their grift, though they aren’t fooling me!). Identify dropping an Ivy League faculty by no means means something, both. It’s all bluster created to offer them false legitimacy.
Claiming {that a} complement can remedy the incurable, reminiscent of autism, ADHD. Don’t even go there.
Huge claims and use of statistics that appear too good to be true. 95% of individuals love this complement? How did the corporate even decide that? Trace: they didn’t.


The usage of earlier than and after pictures and testimonials to ‘show’ efficacy of a product. These are simply faked, and so they present up when an organization has nothing higher to supply when it comes to proof of their product working.
The declare of being safer, extra pure, or equally efficient as precise medicines. We talked about this above.


Obscure claims utilizing phrases or phrases like ‘helps metabolism’ or ‘helps with X’. That is how corporations could make the claims they make, with out triggering the FDA’s consideration. It’s a loophole that many individuals don’t learn about, however now you do!
The usage of influencers to promote the product. This one may be controversial, however I really feel like well-liked influencers utilizing affiliate codes to flood peoples’ social feeds with advertisements for a product is a distraction and made to persuade potential clients that in the event that they use the product, they’ll be younger/engaging/wholesome/well-liked just like the individuals promoting it.
The Risks of Diet Dietary supplements
Whereas all vitamin dietary supplements are marketed as helpful, they’ll typically do extra hurt than good. Among the key dangers embrace:
Lack of Regulation
The U.S. Meals and Drug Administration (FDA) regulates dietary supplements beneath the Dietary Complement Well being and Schooling Act (DSHEA) of 1994, which permits producers to promote merchandise with out proving their security or efficacy. In contrast to prescribed drugs, dietary dietary supplements are usually not required to endure rigorous testing earlier than hitting the market.
Because of this:
Dietary supplements could comprise unlisted or dangerous elements.
Dosages could also be inconsistent or greater than really helpful.
Contaminants reminiscent of heavy metals, pesticides, or prescribed drugs could also be current.
The FDA usually doesn’t get entangled except there has truly been hurt executed to an individual by the complement.


Liver Toxicity and Organ Injury
The liver performs a vital function in processing dietary supplements, breaking down compounds, and detoxifying dangerous substances. Nonetheless, sure dietary supplements comprise elements that may overwhelm or harm liver cells, resulting in:
Hepatotoxicity (liver toxicity): The liver struggles to course of poisonous compounds, resulting in irritation and cell harm.
Acute liver failure: Extreme circumstances the place the liver loses its potential to perform, typically requiring a transplant or leading to demise.
Power liver illness: Lengthy-term harm from repeated publicity to dangerous dietary supplements.
Harmful Interactions with Medicines
Many individuals take dietary supplements alongside prescription medicines with out realizing that sure combos will be poisonous.
For instance, St. John’s Wort can scale back the effectiveness of antidepressants and contraception tablets. Kava and inexperienced tea extracts have been linked to extreme liver harm, particularly when taken with different medicines metabolized by the liver. Vitamin A and iron in extreme doses may cause liver irritation and harm.
Latest Analysis on Complement-Induced Liver Failure
Over the previous decade, scientific research and medical experiences have highlighted a regarding rise in supplement-related liver damage.


The DILIN Research (2014 – Current)
The Drug-Induced Liver Harm Community (DILIN), a U.S.-based analysis initiative, has been monitoring circumstances of drug- and supplement-related liver damage.
Their findings present that:
Natural and dietary dietary supplements account for 20% of liver damage circumstances within the U.S.
The speed of supplement-induced liver harm has elevated from 7% in 2004 to twenty% lately.
Weight-loss and bodybuilding dietary supplements are probably the most generally implicated.
Inexperienced Tea Extracts and Hepatotoxicity
Inexperienced tea extract is a well-liked complement discovered in lots of weight-loss merchandise, however analysis has linked it to extreme liver toxicity.
A 2018 examine within the journal Hepatology discovered that catechins, the lively compounds in inexperienced tea, may cause liver harm in excessive doses. Some circumstances resulted in acute liver failure requiring transplants. A 2022 examine discovered garcinia cambogia, with or with out inexperienced tea (I’ve seen numerous dietary supplements that comprise each of those elements) may cause reasonable to extreme liver damage.


Bodybuilding Dietary supplements and Undisclosed Steroids
Bodybuilding dietary supplements are among the many most harmful, with many containing undeclared anabolic steroids that may trigger liver toxicity.
A 2017 examine in The Journal of Gastroenterology and Hepatology discovered that:
Practically 50% of liver damage circumstances in younger males had been linked to bodybuilding dietary supplements.
Many of those dietary supplements contained unlawful or undisclosed steroid compounds.
Heavy metals like arsenic, micro organism and fungi, banned stimulants like ephedrine, and undeclared medicine like sibutramine (discovered to have cardiac dangers) are just a few examples of what has not too long ago been present in natural vitamin dietary supplements.
Whereas not all dietary supplements are dangerous, it’s important to method them with warning. Right here’s the right way to shield your self:
Do Your Analysis Earlier than Taking Any Complement
Search for scientific research that help the protection and effectiveness of a complement.
Be skeptical of merchandise that promise fast weight reduction, excessive muscle achieve, or “detox” advantages. If one thing is promising to do what no different complement or remedy has executed earlier than (ie fats burners), stroll or scroll proper on by. Whereas a complement won’t be harmful, I additionally think about the monetary impacts of taking something you don’t actually need.


Select Third-Celebration Examined Dietary supplements
Because the FDA doesn’t regulate dietary supplements strictly, search for third-party testing from organizations reminiscent of:
U.S. Pharmacopeia (USP)
NSF Worldwide
ConsumerLab
These certifications be certain that dietary supplements comprise what they declare and don’t have dangerous contaminants.
Keep away from Excessive-Danger Dietary supplements
Among the most harmful dietary supplements embrace:
Inexperienced tea extract (excessive doses)
Kava
Kratom
Bodybuilding dietary supplements with steroids
Weight-loss dietary supplements with “fats burners” or stimulants
Discuss to Your Physician Earlier than Utilizing Dietary supplements
In case you are on medicines, ask your physician about potential complement interactions.
If in case you have liver illness, diabetes, or coronary heart situations, be further cautious with dietary supplements.
In Quick:
Dietary dietary supplements will be useful in some circumstances, however in addition they pose vital dangers—particularly to liver well being. With analysis linking sure dietary supplements to liver failure, it’s essential to learn and selective about what you’re taking.
By selecting third-party examined merchandise, avoiding high-risk dietary supplements, and prioritizing complete meals, you may shield your liver and total well being. At all times seek the advice of with a healthcare skilled earlier than including any new complement to your routine.
Your well being is value greater than a fast repair—keep knowledgeable, and keep protected!
